Safa M1, Saki M2, Matin-rohani Sh3 1. Assistant Professor, Department of psychiatry, Faculty of Medicine, Lorestan University of Medical Sciences 2. Instructor, Department of Nursing, Faculty of Nursing and Midwifery, Lorestan University of Medical Sciences 3. GP Abstract Background: Coronary heart disease as a reason for mortality is occurring with psychiatric disorders. This descriptive- analytic study aims at assess mental health of patients who need to perform coronary angiography and its relationship with drug abuse. Materials and methods: Sampling was done by census and data was collected using General Health Questionnaire and clinical interview. At first, all the patients who needed coronary angiography completed questionnaire and after calculating the patients’ score, psychiatrist visited the patients with score more than 28. Results: Data showed that from 200 patients surveyed in this search, 49.5 percent had mental disorders specially physical signs, distress and sleep disorders, but they were healthy from view point of social functioning and depression. Also, drug abuse is known as an effective factor of mental disorder and rises the chance of mental disorders, so the drug abusers are susceptible to mental disorders 7 times more than the patients with no drug abuse. Conclusion: This study proved that being married plays a positive role on mental health, so the risk of mental disorders in divorcees and widows are 20 times greater than in married patients. Consequently we prefer that patient with coronary heart disease who needs angiography get psychiatric cares and consultation.